LOOPP parallel driver v5.0 (06/13/08 15:45 EDT) with LOOPP v3.0 (compiled Jul 11 2008 17:20:20)
     [NEWSABLE]     [HSHFL]     [ENE]     [NEWALICHOICE]

This is HTML output, the other options are plain text, CASP AL and CASP TS formats.

If an error occured during execution it is logged in plain text version only,
there is no need to look for an error if this file ends with 'DONE' statement.

STARTING:Sun Aug 17 04:04:12 2008 EST

INPUT:
   sim_min =  40.0% minimum sequence identity (%)
   sim_max =  80.0% maximum sequence identity (%)
   len_dif =  20.0% maximum length difference (% of query sequence length) 
                    between query and homolog
   nmax    =  1     maximum number of homologous sequences (including query sequence)
   maxout  =  5     maximum number of outputted matches
   strict  =  0     all alignments will be accepted from LOOPP results
                    for homologs; they will be translated to query sequence 
                    alignments using BLAST results
   casp    =  5     maximum number of outputted matches in CASP format
   align   =  'g'   only corresponding global alignments will be reported
   maxdiff =  50.0% only alignments differing no more than  50.0% from the query
                    sequence will be reported, or when reject=0, corresponding local
                    alignments will be reported
   reject  =  1     alignments shorter more than  50.0% from the query sequence
                    will be rejected
   seccut  =  0.00  structures with sec. str. score below seccut will be rejected
    secdb  = 1      type of secondary structure description: 1 - DSSB, 0 - phi/psi map
   tasktb  = 11111111111111111111  type of initial calculations
   pdbcut  =  60.0% pdb sequence identity threshold (%)
  pdbstop  = 0      stop if PDB structure with similarity above pdbcut found
  domains  = 0      query sequence will be decomposed into putative domains if =1
   maxall  = 300      maximum number of models evaluated in the second stage       
   refstr  = 0      if equal to 1 rmsd distances between all hits and a reference structure
                   will be reported
   maxpdb  = 5      number of top PDB hits added to the second stage scoring 
   maxdyn  = 5      number of dynamic domain entries from database added to the second stage scoring 
 beautify  = 0      use pdb beautifier 
rmsdtables  = 1     compute rmsd tables between hits 

   local LOOPP/BLAST database will be used

   input file T0464
    --> 89 residues, sequence name: T0464
   Database: T:\CBSU\blastdb\20080108\nr


 -> 7 homolog sequences with sequence identity from  40.0% to  80.0% satisfying length constraints found
 -> 0 representatives will be used in search (nmax=1 including query sequence)
 Histogram of all homolog sequences found by BLAST (e-value cutoff 0.01, length constr.) by sequence identity:
00%-10% 10%-20% 20%-30% 30%-40% 40%-50% 50%-60% 60%-70% 70%-80% 80%-90% 90%-100%
0 0 0 0 3 0 0 4 0 2
RESULTS secondary structure prediction shows 20.22% helical, 11.24% extended and 68.54% loops/other homologs/domains used: 0 query sequence T0464 all homologs found total number of entries processed: 76 Amino acid profile calculated versus nr database is here (Amino acid profile BLAST run output is here) Results of BLAST versus pdbaa database using the nr profile are here (Results of BLAST versus pdbaa database with no profile are here) Transitive BLAST output calculted with this profile is here Phase 1 scoring data: input and output Phase 2 scoring data: input and output HITS: table legend no name SCOP SCOP_stat confidence score homolog hits length seq. align ENE TE13 old CGenergy SIFT2 tma1 tma2 |-------OPTM------| |-------SEQ (global)-------| |-------SEQ (local)-------| |-------TRD (global)-------| |-------TRD (local)-------| |-------TRS (global)-------| |-------TRS (local)-------| |-------TSS (global)-------| |-------TSS (local)-------| |-------TSC (global)-------| |-------TSC (local)-------| |-------PSM (global)-------| |-------PSM (local)-------| |-------SRF (global)-------| |-------SRF (local)-------| |-------TBLS------| |-------KMER------| |-------CFTR------| |-------TBSS------| |-------SBLS------| sec. str. (%) ident. src. all-atom all-atom score all-atom all-atom all-atom all-atom r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy r-energy energy r-energy energy r-energy energy r-energy energy r-energy energy pos. comp. 1 a.4.5.32.2_A a.4.5.32 4.1.1.1 LOW -22.044 0 1 55.06% 28.57% OPTM -41.843 -89.560 0.394 0.564 0.190 0.615 0.735 4.920 -15.6 1.370 14.000 -9.5 1.320 11.000 -65.0 -0.760 -0.410 21.3 -1.420 -0.200 -9.9 -0.500 -4.520 30.2 -1.230 -0.180 -9.0 2.060 1.180 11.1 3.710 4.270 -23.0 -30.000 1.000 -17.0 -30.000 4.000 -42.0 2.630 41.000 -10.0 3.080 17.000 -64.0 0.390 1.000 52.0 0.030 -1.000 -19.0 5.000 5.0 1.992 -41.1 -17.000 143.0 5.000 5.0 5.000 5.0 0.62 0.26 2 2JNY_A not_found 31.31.31.31 NONE -999.000 0 1 68.54% 21.62% OPTM -94.613 -89.440 1.043 0.329 0.174 0.718 0.852 3.820 -14.4 4.350 54.000 -54.0 3.730 44.500 -87.0 -0.150 -0.900 16.8 -0.070 -0.450 -9.6 4.400 8.390 13.4 5.490 7.850 -16.8 6.510 5.300 -1.0 6.160 2.330 -26.3 -30.000 4.000 -24.0 -30.000 0.000 -44.0 5.370 85.500 -52.5 6.880 54.000 -79.0 -0.680 -4.000 70.0 0.640 0.000 -16.0 5.000 -7.5 -10.881 -58.6 0.000 -9.3e+061 5.000 -7.4 0.681 -5.1 0.36 0.25 3 2JR6_A not_found 31.31.31.31 NONE -999.000 0 1 60.67% 20.37% OPTM -75.384 -54.010 0.920 0.492 0.148 0.641 0.767 0.010 -13.3 2.780 25.000 -31.0 3.690 28.000 -79.0 -0.290 -1.710 8.9 0.380 0.420 -15.5 3.050 5.530 8.7 1.610 0.320 -15.1 4.470 4.890 -7.0 3.710 -0.620 -24.3 -30.000 -4.000 -30.0 -30.000 -7.000 -43.0 4.370 59.000 -39.0 6.120 50.000 -79.0 0.420 4.000 36.0 2.750 5.000 -26.0 5.000 -7.7 -5.024 -51.9 0.000 -9.3e+061 5.000 -7.7 5.000 -3.2 0.45 0.46 4 2JS4_A not_found 31.31.31.31 NONE -999.000 0 1 61.80% 18.18% OPTM -76.223 -59.420 0.863 0.555 0.176 0.719 0.904 2.880 -14.3 1.130 -2.500 -29.5 3.060 27.000 -86.0 -0.100 -1.100 8.9 0.070 0.570 -9.6 1.880 4.240 9.2 4.610 6.060 -15.0 1.640 -2.430 -6.4 4.540 1.260 -26.9 -30.000 -6.000 -33.0 -30.000 -6.000 -42.0 4.270 47.000 -44.0 5.950 45.000 -77.0 0.660 3.000 70.0 1.470 1.000 -19.0 5.000 -5.0 -9.044 -62.8 0.000 -9.3e+061 5.000 -5.0 5.000 -1.2 0.39 0.30 5 1W6V_A d.324.1.1 14.1.1.1 NONE -999.000 0 1 83.15% 18.92% OPTM -95.158 -72.050 0.795 0.563 0.299 0.524 0.798 4.000 -16.6 1.490 30.000 16.0 0.760 -0.500 -54.5 -0.080 0.450 55.6 -1.270 -2.220 -15.3 -0.350 2.560 69.0 2.080 4.180 -15.1 3.310 13.770 22.8 5.660 6.700 -32.8 -30.000 13.000 -42.0 -30.000 1.000 -56.0 1.330 15.000 55.0 5.370 32.000 -57.0 2.000 11.000 5.0 1.460 7.000 -36.0 5.000 0.8 -0.253 -84.2 0.000 -9.3e+061 5.000 0.9 1.114 0.0 0.54 0.97 RMSD table between hits (RMSDs are shaded according to similarity, up to 10Å )

1

2

3

4

5

1

0.00

11.15

8.14

7.88

12.20

2

11.15

0.00

5.09

6.10

12.36

3

8.14

5.09

0.00

6.05

12.36

4

7.88

6.10

6.05

0.00

12.13

5

12.20

12.36

12.36

12.13

0.00



Similarity table for hits: percentage of chain fitting below 3Å RMSD
(Cells are shaded according to similarity starting at 30%)

1

2

3

4

5

1

100.00

28.95

64.71

58.82

32.65

2

28.95

100.00

71.70

90.57

26.98

3

64.71

71.70

100.00

75.93

35.71

4

58.82

90.57

75.93

100.00

40.48

5

32.65

26.98

35.71

40.48

100.00



Similarity table for hits: percentage of chain fitting below 6Å RMSD
(Cells are shaded according to similarity starting at 50%)

1

2

3

4

5

1

100.00

44.74

88.24

88.24

73.47

2

44.74

100.00

100.00

98.11

41.27

3

88.24

100.00

100.00

98.15

64.29

4

88.24

98.11

98.15

100.00

61.90

5

73.47

41.27

64.29

61.90

100.00





ALIGNMENTS

--> hit 1 [All-atom model (PDB)] [view all-atom model (PDB) with Chime] [PIR alignment file] [PDB file (backbone only)] [view PDB file (backbone only) with Chime] [hit list]


  secondary structure: 45.76% helical,  0.00% extended, 54.24% loops/other (query: 20.22% 11.24% 68.54%)

  SCOP classification:  [All alpha proteins]/[DNA/RNA-binding 3-helical bundle]

 name                SCOP           SCOP_stat         confidence    score homolog  hits  length   seq.   align    ENE             TE13        old        CGenergy      SIFT2        tma1         tma2      |-------OPTM------| |-------SEQ  (global)-------| |-------SEQ   (local)-------| |-------TRD  (global)-------| |-------TRD   (local)-------| |-------TRS  (global)-------| |-------TRS   (local)-------| |-------TSS  (global)-------| |-------TSS   (local)-------| |-------TSC  (global)-------| |-------TSC   (local)-------| |-------PSM  (global)-------| |-------PSM   (local)-------| |-------SRF  (global)-------| |-------SRF   (local)-------| |-------TBLS------| |-------KMER------| |-------CFTR------| |-------TBSS------| |-------SBLS------|  sec. str.
                                                                                          (%)    ident.  src.    all-atom      all-atom      score      all-atom     all-atom     all-atom     all-atom   r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy    zscore  r-energy    energy  r-energy    energy  r-energy    energy  r-energy    energy  r-energy    energy  r-energy    energy    pos. comp.
a.4.5.32.2_A         a.4.5.32      4.1.1.1                 LOW   -22.044     0       1  55.06%  28.57%   OPTM      -41.843      -89.560        0.394        0.564        0.190        0.615        0.735      4.920     -15.6     1.370    14.000      -9.5     1.320    11.000     -65.0    -0.760    -0.410      21.3    -1.420    -0.200      -9.9    -0.500    -4.520      30.2    -1.230    -0.180      -9.0     2.060     1.180      11.1     3.710     4.270     -23.0   -30.000     1.000     -17.0   -30.000     4.000     -42.0     2.630    41.000     -10.0     3.080    17.000     -64.0     0.390     1.000      52.0     0.030    -1.000     -19.0     5.000       5.0     1.992     -41.1   -17.000     143.0     5.000       5.0     5.000       5.0    0.62  0.26

alignment source: OPTM
            HHHHHH----------       ------HHHHHHHHHH-----------------
Query:    3 RKLLHLLCSPDTRQPL-------SLLESKGLEALNKAIASGTVQRADGSIQNQSLH   51
Sbjct:   30 KKIIKILQN-DGKAPLREISKITGLAESTIHERIRKLRESGVIKKFTAIIDPEALG   84
            HHHHHH--- ----HHHHHHH-------HHHHHHHHHH-----------------G

49 residues (55.06%) of query sequence aligned


--> hit 2 [All-atom model (PDB)] [view all-atom model (PDB) with Chime] [PIR alignment file] [PDB file (backbone only)] [view PDB file (backbone only) with Chime] [hit list] secondary structure: 0.00% helical, 28.33% extended, 71.67% loops/other (query: 20.22% 11.24% 68.54%) SCOP classification: name SCOP SCOP_stat confidence score homolog hits length seq. align ENE TE13 old CGenergy SIFT2 tma1 tma2 |-------OPTM------| |-------SEQ (global)-------| |-------SEQ (local)-------| |-------TRD (global)-------| |-------TRD (local)-------| |-------TRS (global)-------| |-------TRS (local)-------| |-------TSS (global)-------| |-------TSS (local)-------| |-------TSC (global)-------| |-------TSC (local)-------| |-------PSM (global)-------| |-------PSM (local)-------| |-------SRF (global)-------| |-------SRF (local)-------| |-------TBLS------| |-------KMER------| |-------CFTR------| |-------TBSS------| |-------SBLS------| sec. str. (%) ident. src. all-atom all-atom score all-atom all-atom all-atom all-atom r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy r-energy energy r-energy energy r-energy energy r-energy energy r-energy energy pos. comp. 2JNY_A not_found 31.31.31.31 NONE -999.000 0 1 68.54% 21.62% OPTM -94.613 -89.440 1.043 0.329 0.174 0.718 0.852 3.820 -14.4 4.350 54.000 -54.0 3.730 44.500 -87.0 -0.150 -0.900 16.8 -0.070 -0.450 -9.6 4.400 8.390 13.4 5.490 7.850 -16.8 6.510 5.300 -1.0 6.160 2.330 -26.3 -30.000 4.000 -24.0 -30.000 0.000 -44.0 5.370 85.500 -52.5 6.880 54.000 -79.0 -0.680 -4.000 70.0 0.640 0.000 -16.0 5.000 -7.5 -10.881 -58.6 0.000 -9.3e+061 5.000 -7.4 0.681 -5.1 0.36 0.25 alignment source: OPTM +++ there is a problem with all-atom model, click here for details -----------HHHHHHHHHH-------------------EE-----EEEEE----EEE--HH----------- Query: 14 TRQPLSLLESKGLEALNKAIASGTVQRADGSIQNQSLHEALITRDRKQVFRIEDSIPVLLPEEAIATIQIANFP 87 Sbjct: 1 MSLDPQLLEV------------LACPKDKGPLRYLESEQLLVNERLNLAYRIDDGIPVLLIDEA-TEWTPNNLE 61 ---------- ----------EEE----EEEE----EEEEEE--EE------- EE------- 61 residues (68.54%) of query sequence aligned
--> hit 3 [All-atom model (PDB)] [view all-atom model (PDB) with Chime] [PIR alignment file] [PDB file (backbone only)] [view PDB file (backbone only) with Chime] [hit list] secondary structure: 7.46% helical, 25.37% extended, 67.16% loops/other (query: 20.22% 11.24% 68.54%) SCOP classification: name SCOP SCOP_stat confidence score homolog hits length seq. align ENE TE13 old CGenergy SIFT2 tma1 tma2 |-------OPTM------| |-------SEQ (global)-------| |-------SEQ (local)-------| |-------TRD (global)-------| |-------TRD (local)-------| |-------TRS (global)-------| |-------TRS (local)-------| |-------TSS (global)-------| |-------TSS (local)-------| |-------TSC (global)-------| |-------TSC (local)-------| |-------PSM (global)-------| |-------PSM (local)-------| |-------SRF (global)-------| |-------SRF (local)-------| |-------TBLS------| |-------KMER------| |-------CFTR------| |-------TBSS------| |-------SBLS------| sec. str. (%) ident. src. all-atom all-atom score all-atom all-atom all-atom all-atom r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy r-energy energy r-energy energy r-energy energy r-energy energy r-energy energy pos. comp. 2JR6_A not_found 31.31.31.31 NONE -999.000 0 1 60.67% 20.37% OPTM -75.384 -54.010 0.920 0.492 0.148 0.641 0.767 0.010 -13.3 2.780 25.000 -31.0 3.690 28.000 -79.0 -0.290 -1.710 8.9 0.380 0.420 -15.5 3.050 5.530 8.7 1.610 0.320 -15.1 4.470 4.890 -7.0 3.710 -0.620 -24.3 -30.000 -4.000 -30.0 -30.000 -7.000 -43.0 4.370 59.000 -39.0 6.120 50.000 -79.0 0.420 4.000 36.0 2.750 5.000 -26.0 5.000 -7.7 -5.024 -51.9 0.000 -9.3e+061 5.000 -7.7 5.000 -3.2 0.45 0.46 alignment source: OPTM -------------------EE-----EEEEE----EEE-- HH------------ Query: 35 SGTVQRADGSIQNQSLHEALITRDRKQVFRIEDSIPVLLP-------EEAIATIQIANFPD 88 Sbjct: 8 ILVCPVTKGRLEYHQDKQELWSRQAKLAYPIKDGIPYMLENEARPLSEEELKALEHHHHHH 68 ----------EEE----EEEE----EEEEEE--EE-------EE--HHHHH---------H 54 residues (60.67%) of query sequence aligned
--> hit 4 [All-atom model (PDB)] [view all-atom model (PDB) with Chime] [PIR alignment file] [PDB file (backbone only)] [view PDB file (backbone only) with Chime] [hit list] secondary structure: 0.00% helical, 26.09% extended, 73.91% loops/other (query: 20.22% 11.24% 68.54%) SCOP classification: name SCOP SCOP_stat confidence score homolog hits length seq. align ENE TE13 old CGenergy SIFT2 tma1 tma2 |-------OPTM------| |-------SEQ (global)-------| |-------SEQ (local)-------| |-------TRD (global)-------| |-------TRD (local)-------| |-------TRS (global)-------| |-------TRS (local)-------| |-------TSS (global)-------| |-------TSS (local)-------| |-------TSC (global)-------| |-------TSC (local)-------| |-------PSM (global)-------| |-------PSM (local)-------| |-------SRF (global)-------| |-------SRF (local)-------| |-------TBLS------| |-------KMER------| |-------CFTR------| |-------TBSS------| |-------SBLS------| sec. str. (%) ident. src. all-atom all-atom score all-atom all-atom all-atom all-atom r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy r-energy energy r-energy energy r-energy energy r-energy energy r-energy energy pos. comp. 2JS4_A not_found 31.31.31.31 NONE -999.000 0 1 61.80% 18.18% OPTM -76.223 -59.420 0.863 0.555 0.176 0.719 0.904 2.880 -14.3 1.130 -2.500 -29.5 3.060 27.000 -86.0 -0.100 -1.100 8.9 0.070 0.570 -9.6 1.880 4.240 9.2 4.610 6.060 -15.0 1.640 -2.430 -6.4 4.540 1.260 -26.9 -30.000 -6.000 -33.0 -30.000 -6.000 -42.0 4.270 47.000 -44.0 5.950 45.000 -77.0 0.660 3.000 70.0 1.470 1.000 -19.0 5.000 -5.0 -9.044 -62.8 0.000 -9.3e+061 5.000 -5.0 5.000 -1.2 0.39 0.30 alignment source: OPTM -------------------EE-----EEEEE----EEE--HH------------- Query: 35 SGTVQRADGSIQNQSLHEALITRDRKQVFRIEDSIPVLLPEEAIATIQIANFPDK 89 Sbjct: 8 ILVCPVCKGRLEFQRAQAELVCNADRLAFPVRDGVPIMLEAEARSLDAEAPAQPS 62 ---------EEEE----EEEE----EEEEEE--EE-------EE----------- 55 residues (61.80%) of query sequence aligned
--> hit 5 [All-atom model (PDB)] [view all-atom model (PDB) with Chime] [PIR alignment file] [PDB file (backbone only)] [view PDB file (backbone only) with Chime] [hit list] secondary structure: 20.83% helical, 10.42% extended, 68.75% loops/other (query: 20.22% 11.24% 68.54%) SCOP classification: [Alpha and beta proteins (a+b)]/[DUSP-like] name SCOP SCOP_stat confidence score homolog hits length seq. align ENE TE13 old CGenergy SIFT2 tma1 tma2 |-------OPTM------| |-------SEQ (global)-------| |-------SEQ (local)-------| |-------TRD (global)-------| |-------TRD (local)-------| |-------TRS (global)-------| |-------TRS (local)-------| |-------TSS (global)-------| |-------TSS (local)-------| |-------TSC (global)-------| |-------TSC (local)-------| |-------PSM (global)-------| |-------PSM (local)-------| |-------SRF (global)-------| |-------SRF (local)-------| |-------TBLS------| |-------KMER------| |-------CFTR------| |-------TBSS------| |-------SBLS------| sec. str. (%) ident. src. all-atom all-atom score all-atom all-atom all-atom all-atom r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy zscore r-energy energy r-energy energy r-energy energy r-energy energy r-energy energy r-energy energy pos. comp. 1W6V_A d.324.1.1 14.1.1.1 NONE -999.000 0 1 83.15% 18.92% OPTM -95.158 -72.050 0.795 0.563 0.299 0.524 0.798 4.000 -16.6 1.490 30.000 16.0 0.760 -0.500 -54.5 -0.080 0.450 55.6 -1.270 -2.220 -15.3 -0.350 2.560 69.0 2.080 4.180 -15.1 3.310 13.770 22.8 5.660 6.700 -32.8 -30.000 13.000 -42.0 -30.000 1.000 -56.0 1.330 15.000 55.0 5.370 32.000 -57.0 2.000 11.000 5.0 1.460 7.000 -36.0 5.000 0.8 -0.253 -84.2 0.000 -9.3e+061 5.000 0.9 1.114 0.0 0.54 0.97 alignment source: OPTM HHHHHH------- ---------HHHHHHHHHH----------------- --EE-----EEEE E----EEE-- Query: 3 RKLLHLLCSPDTR-QPLSLLESKGLEALNKAIASGTVQRADGSIQNQSLH----EALITRDRKQVFR---IEDSIPVLLP 74 Sbjct: 14 SDIATLLKTSLRKGDTWYLVDSRWFKQWKKYVGFDSWDKYQMGDQNVYPGPIDNSGLLKDGDAQSLKEHLIDELDYILLP 93 HHHHHH--------EEEEEEHHHHHHHHHHH-------------------------------------------EEEE-H HH Query: 75 EE 76 Sbjct: 94 TE 95 HH 74 residues (83.15%) of query sequence aligned
DONE: Sun Aug 17 05:17:11 2008 EST